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General Surgery · Gastrointestinal surgery: spontaneous bacterial peritonitis
Sample itemA cirrhotic patient with ascites has fever and diffuse abdominal tenderness. Diagnostic paracentesis shows an ascitic neutrophil count of 400 per cubic mm. What is the treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Intravenous third-generation cephalosporin with albumin
An ascitic neutrophil count of 250 or more per cubic mm diagnoses spontaneous bacterial peritonitis, treated with a third-generation cephalosporin and albumin to protect the kidneys. Laparotomy is not needed when there is no perforation. Long-term prophylaxis follows.
Option by option
A. Metronidazole alone
Metronidazole alone does not cover the usual Gram-negative enteric organisms.
B. Large-volume paracentesis alone
Paracentesis alone does not treat the infection.
C. Intravenous third-generation cephalosporin with albumin (correct)
Correct. Cephalosporin plus albumin is standard treatment.
D. Emergency laparotomy
The peritonitis is primary and not due to perforation, so surgery does not help.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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