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General Surgery · Gastrointestinal surgery: actinomycosis
Sample itemA man with poor dental hygiene has a chronic indurated swelling at the angle of the jaw with multiple discharging sinuses. The discharge contains yellow granules, and Gram stain shows branching filaments that are not acid-fast. What is the treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Prolonged high-dose penicillin
Cervicofacial actinomycosis, caused by anaerobic Actinomyces, produces sulphur granules and responds to prolonged high-dose penicillin, with drainage of abscesses. The filaments are non-acid-fast, which excludes tuberculosis and Nocardia. It is not a malignancy.
Option by option
A. Wide excision with neck dissection
The lesion is infective, so cancer surgery is wrong.
B. Antitubercular therapy
The organism is not acid-fast, so antitubercular drugs are not indicated.
C. Prolonged high-dose penicillin (correct)
Correct. Penicillin for many weeks is the treatment of choice.
D. Itraconazole
Antifungal drugs do not treat this bacterial infection.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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