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Radiology · Neuroimaging: MRI ageing of haemorrhage
Sample itemA haematoma in the brain appears hyperintense on T1-weighted images and hyperintense on T2-weighted images, without a dark rim. In which stage of evolution is this haematoma?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Late subacute, with extracellular methaemoglobin
Extracellular methaemoglobin in the late subacute stage, from about one week to some weeks, is bright on both T1 and T2. Intracellular methaemoglobin in the early subacute stage is bright on T1 but dark on T2. Acute deoxyhaemoglobin is dark on T2, and chronic haemosiderin forms a dark rim.
Option by option
A. Late subacute, with extracellular methaemoglobin (correct)
Correct. Extracellular methaemoglobin is bright on T1 and T2.
B. Chronic, with haemosiderin
Haemosiderin is dark on all sequences and rims the old lesion.
C. Acute, with intracellular deoxyhaemoglobin
Deoxyhaemoglobin is isointense on T1 and dark on T2.
D. Hyperacute, with oxyhaemoglobin
Oxyhaemoglobin in the hyperacute phase is isointense on T1 and bright on T2.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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