General anatomy and histology: practice question

A Anatomy question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anatomy · General anatomy and histology

Sample item

A young man in the third week of untreated enteric fever has sudden peritonitis. At laparotomy the perforation is most likely in which part of the gut because of the lymphoid tissue there?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Terminal ileum

Salmonella Typhi invades through M cells over Peyer's patches, which are most numerous in the terminal ileum. Ulceration along these patches leads to haemorrhage or perforation in the third week.

Option by option

  • A. Terminal ileum (correct)

    Correct. Peyer's patches are densest in the terminal ileum and are the site of typhoid ulcers.

  • B. Second part of the duodenum

    The duodenum has Brunner glands and few lymphoid aggregates.

  • C. Sigmoid colon

    The sigmoid colon has solitary follicles but not aggregated Peyer's patches.

  • D. Proximal jejunum

    The proximal jejunum has plicae circulares and almost no patches.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Anatomy questions

Questions about this Anatomy question

What is the answer to this Anatomy question?

The best answer is A, Terminal ileum. Salmonella Typhi invades through M cells over Peyer's patches, which are most numerous in the terminal ileum.

Why is "Second part of the duodenum" not the answer?

The duodenum has Brunner glands and few lymphoid aggregates.

Why is "Sigmoid colon" not the answer?

The sigmoid colon has solitary follicles but not aggregated Peyer's patches.

Why is "Proximal jejunum" not the answer?

The proximal jejunum has plicae circulares and almost no patches.

What concept does this question test?

It tests General anatomy and histology in Anatomy. Ulceration along these patches leads to haemorrhage or perforation in the third week.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study General anatomy and histology?

Learn every nerve by its route, its muscles and what a lesion looks like at the bedside. That one habit answers a large share of questions. Then use the flashcards and the other Anatomy questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.