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ENT · Ear and audiology: cholesterol granuloma
Sample itemA 40-year-old man has mild conductive hearing loss and a dark blue bulging tympanic membrane, with no history of trauma. MRI of the temporal bone shows a middle ear lesion that is bright on both T1 and T2 sequences. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Cholesterol granuloma
A cholesterol granuloma contains blood breakdown products and cholesterol crystals, giving a blue drum and high signal on both T1 and T2. A cholesteatoma is dull on T1 with restricted diffusion. A glomus tumour is a red vascular mass that enhances.
Option by option
A. Tympanosclerosis
Tympanosclerosis gives white chalky plaques in the drum, not a blue bulging membrane.
B. Cholesteatoma
A cholesteatoma is intermediate to low on T1 and shows restricted diffusion, and the drum is white or retracted.
C. Glomus tympanicum
A glomus tympanicum is a red, pulsatile mass with intense enhancement and pulsatile tinnitus.
D. Cholesterol granuloma (correct)
Correct. A blue drum with high T1 and high T2 signal is typical of a cholesterol granuloma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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