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Radiology · Nuclear medicine: complex regional pain syndrome
Sample itemA woman develops pain, swelling and allodynia of the hand six weeks after a wrist fracture. A radiograph shows patchy periarticular osteopenia. What is the typical finding on a three-phase bone scan?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Diffusely increased periarticular uptake on delayed images
Early complex regional pain syndrome causes increased blood flow and pool phases and diffusely increased periarticular uptake in the affected limb on delayed images. The pattern is not limited to the fracture. Absent uptake suggests avascular bone or occlusion.
Option by option
A. Uptake confined to the fracture site only
Uptake limited to the fracture reflects ordinary healing and not CRPS.
B. Diffusely increased periarticular uptake on delayed images (correct)
Correct. Diffuse periarticular delayed uptake is typical of early CRPS.
C. Absent uptake in all three phases
Absent uptake in all phases suggests vascular occlusion.
D. A single focal photopenic defect at the fracture
A photopenic defect suggests avascular bone or tumour necrosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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