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Orthopaedics · Crystal arthropathy
Sample itemWhat do the crystals in synovial fluid of gout look like under polarised light?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Needle-shaped and negatively birefringent
Gout is caused by monosodium urate crystals, which are needle-shaped and negatively birefringent (yellow when parallel to the compensator axis). Pseudogout shows calcium pyrophosphate crystals, which are rhomboid and weakly positively birefringent.
Option by option
A. Rhomboid and positively birefringent
Rhomboid, positively birefringent crystals indicate pseudogout.
B. Needle-shaped and negatively birefringent (correct)
Correct. This is the diagnostic crystal appearance of gout.
C. Bipyramidal and non-birefringent
Calcium oxalate crystals are bipyramidal.
D. Rectangular plates
Cholesterol crystals are rectangular plates.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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