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Psychiatry · Psychopharmacology
Sample itemLithium use during the first trimester of pregnancy is associated with which congenital anomaly?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Ebstein's anomaly
Lithium is linked with Ebstein's anomaly of the tricuspid valve. Valproate is linked with neural tube defects and thalidomide with phocomelia.
Option by option
A. Neural tube defects
Valproate and carbamazepine are linked to neural tube defects.
B. Ebstein's anomaly (correct)
Correct.
C. Phocomelia
Phocomelia is linked to thalidomide.
D. Cleft lip
Cleft lip is linked with phenytoin and other exposures.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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