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Radiology · Contrast agents
Sample itemA patient with sudden severe epigastric pain is suspected of having a perforated duodenal ulcer, and a contrast study is requested to show the leak. Which agent should be used?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Water-soluble iodinated contrast
When perforation is suspected, water-soluble iodinated contrast is used because it is absorbed from the peritoneum and is much less harmful if it leaks. Barium in the peritoneal cavity can cause severe peritonitis and adhesions.
Option by option
A. Gadolinium chelate
Gadolinium chelates are MRI contrast agents and are not used for fluoroscopic studies.
B. Ethiodised oil
Ethiodised oil is an oil-based agent used for lymphography and hysterosalpingography, not for gastrointestinal leak studies.
C. Water-soluble iodinated contrast (correct)
Correct. It is safe if it escapes into the peritoneal cavity.
D. Barium sulphate suspension
Barium leaking into the peritoneum can cause severe peritonitis and adhesions.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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