The mnemonic
The 3 Ps
What each word stands for
- PParathyroid hyperplasia or adenoma
- PPituitary adenoma
- PPancreatic endocrine tumours
Why it matters clinically
Primary hyperparathyroidism is usually the first manifestation. The MEN1 gene encodes menin.
Where it stops being reliable
MEN2A/2B involve medullary thyroid carcinoma and phaeochromocytoma, not the same set; do not blend them.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.