The mnemonic
ALCAN
What each word stands for
- AAllopurinol
- LLamotrigine
- CCarbamazepine
- AAntibiotics, particularly sulfonamides
- NNevirapine and NSAIDs such as oxicams
Why it matters clinically
Helps recall the likely culprit drug.
Where it stops being reliable
Other drugs, including phenytoin, also cause SJS/TEN.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.