The mnemonic
HARMED
What each word stands for
- HHyperthermia
- AAutonomic instability
- RRigidity
- MMyoclonus
- EEncephalopathy
- DDiarrhoea
Why it matters clinically
Identifies a toxic combination, such as SSRIs with MAO inhibitors or tramadol.
Where it stops being reliable
Does not state the cause and not all features appear together.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.