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Pathology · Autoimmunity
Sample itemWhich mechanism causes Graves disease?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Stimulating antibodies to TSH receptor
This item reviews Autoimmunity; Stimulating antibodies to TSH receptor is the best answer because it directly fits the mechanism or morphology described.
Option by option
A. Loss of collagen
Loss of collagen is not supported by the stated finding.
B. Immune complexes only
Immune complexes only is plausible but is not the best fit here.
C. T-cell destruction only
T-cell destruction only does not match the key mechanism or pattern.
D. Stimulating antibodies to TSH receptor (correct)
Correct. Stimulating antibodies to TSH receptor is supported by the defining finding.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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