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Pathology · Hematopathology
Sample itemWhat translocation is associated with chronic myeloid leukemia?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. t(9;22)
The defining Hematopathology relationship supports t(9;22); it is the option that most directly explains the biochemical pathway or pathological process in the stem.
Option by option
A. t(8;14)
t(8;14) does not match the stated hematopathology mechanism.
B. t(9;22) (correct)
Correct. t(9;22) is the appropriate conclusion from the key feature.
C. t(14;18)
t(14;18) does not account for the central finding in this item.
D. t(15;17)
t(15;17) is relevant in a different context but is not supported here.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.