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Pathology · Cell adaptation
Sample itemWhat adaptation occurs when bronchial epithelium becomes squamous in smokers?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Metaplasia
Chronic irritation can cause squamous metaplasia, a reversible replacement of one mature epithelial type by another better able to withstand stress.
Option by option
A. Apoptosis
Apoptosis is programmed cell death.
B. Metaplasia (correct)
Correct: replacement of ciliated epithelium by squamous cells is metaplasia.
C. Necrosis
Necrosis is uncontrolled cell death with inflammation.
D. Hyperplasia only
Hyperplasia increases cell number without changing cell type.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.