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Pathology · Inflammation
Sample itemWhat is the main role of macrophages in chronic inflammation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Phagocytosis and cytokine release
Macrophages ingest debris and microbes, present antigen, release cytokines, and coordinate repair, making them central effector cells in chronic inflammation.
Option by option
A. Myelin formation
Myelin is formed by glial cells.
B. Platelet aggregation
Platelet aggregation is part of hemostasis.
C. Oxygen transport
Oxygen transport is performed by erythrocytes.
D. Phagocytosis and cytokine release (correct)
Correct: macrophages phagocytose and coordinate chronic inflammatory responses.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.