Calcification: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Calcification

Sample item

What is metastatic calcification?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Calcium deposition in normal tissue from hypercalcemia

Metastatic calcification occurs in otherwise normal tissues when hypercalcemia or hyperphosphatemia causes calcium salt deposition, often in kidney, lung, or gastric mucosa.

Option by option

  • A. Calcium deposition in normal tissue from hypercalcemia (correct)

    Correct: metastatic calcification reflects elevated serum minerals in normal tissue.

  • B. Calcium in injured tissue with normal calcium

    Dystrophic calcification occurs in injured tissue with normal serum calcium.

  • C. Bone remodeling only

    Bone remodeling is physiologic and not metastatic calcification.

  • D. Loss of mineral from bone

    Loss of bone mineral is demineralization, not calcification.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is A, Calcium deposition in normal tissue from hypercalcemia. Metastatic calcification occurs in otherwise normal tissues when hypercalcemia or hyperphosphatemia causes calcium salt deposition, often in kidney, lung, or gastric mucosa.

Why is "Calcium in injured tissue with normal calcium" not the answer?

Dystrophic calcification occurs in injured tissue with normal serum calcium.

Why is "Bone remodeling only" not the answer?

Bone remodeling is physiologic and not metastatic calcification.

Why is "Loss of mineral from bone" not the answer?

Loss of bone mineral is demineralization, not calcification.

What concept does this question test?

It tests Calcification in Pathology. The correct option holds because: Correct: metastatic calcification reflects elevated serum minerals in normal tissue.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Calcification?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.