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Psychiatry · Substance use: alcohol withdrawal
Sample itemA hospitalized patient who stopped heavy alcohol use 48 hours ago is tremulous, diaphoretic, hypertensive, and sees insects crawling on the wall. What is the most appropriate medication class for this syndrome?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Benzodiazepines
Benzodiazepines are first-line treatment for alcohol withdrawal because they reduce withdrawal severity and prevent seizures and delirium tremens. Antipsychotics may occasionally be adjuncts but do not replace adequate benzodiazepine treatment.
Option by option
A. Benzodiazepines (correct)
Correct. Benzodiazepines provide cross-tolerance at GABA-A receptors and prevent severe complications.
B. Antipsychotics as monotherapy
Antipsychotic monotherapy does not prevent withdrawal seizures and can lower seizure threshold.
C. Selective serotonin reuptake inhibitors
SSRIs have no role in immediate control of alcohol withdrawal.
D. Opioid antagonists
Opioid antagonists are used in opioid-related care, not acute alcohol withdrawal.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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