Endocrine physiology: insulin: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Endocrine physiology: insulin

Sample item

Insulin promotes uptake of glucose into skeletal muscle chiefly by translocating which transporter to the cell membrane?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. GLUT4

GLUT4 is insulin responsive in skeletal muscle and adipose tissue. GLUT2 is found in liver and pancreatic beta cells, while GLUT1 provides basal uptake in many tissues.

Option by option

  • A. GLUT2

    GLUT2 is a high-capacity glucose transporter in liver and beta cells.

  • B. GLUT4 (correct)

    Correct. Insulin recruits GLUT4 to muscle and adipocyte membranes.

  • C. SGLT1

    SGLT1 cotransports sodium and glucose in intestine.

  • D. GLUT1

    GLUT1 mediates basal glucose transport, including across the blood-brain barrier.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is B, GLUT4. GLUT4 is insulin responsive in skeletal muscle and adipose tissue.

Why is "GLUT2" not the answer?

GLUT2 is a high-capacity glucose transporter in liver and beta cells.

Why is "SGLT1" not the answer?

SGLT1 cotransports sodium and glucose in intestine.

Why is "GLUT1" not the answer?

GLUT1 mediates basal glucose transport, including across the blood-brain barrier.

What concept does this question test?

It tests Endocrine physiology: insulin in Physiology. GLUT2 is found in liver and pancreatic beta cells, while GLUT1 provides basal uptake in many tissues.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Endocrine physiology: insulin?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.