Neoplasia: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Neoplasia

Sample item

What is carcinoma in situ?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Full-thickness epithelial atypia without basement-membrane invasion

Carcinoma in situ shows severe epithelial dysplasia through the full thickness but has not breached the basement membrane to invade stroma.

Option by option

  • A. Inflammation limited to mucosa

    Inflammation is not carcinoma in situ.

  • B. Full-thickness epithelial atypia without basement-membrane invasion (correct)

    Correct: absence of invasion defines in-situ carcinoma.

  • C. Benign glandular hyperplasia

    Hyperplasia lacks severe malignant atypia.

  • D. Metastatic cancer in lymph node

    Lymph-node spread is metastatic disease.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is B, Full-thickness epithelial atypia without basement-membrane invasion. Carcinoma in situ shows severe epithelial dysplasia through the full thickness but has not breached the basement membrane to invade stroma.

Why is "Inflammation limited to mucosa" not the answer?

Inflammation is not carcinoma in situ.

Why is "Benign glandular hyperplasia" not the answer?

Hyperplasia lacks severe malignant atypia.

Why is "Metastatic cancer in lymph node" not the answer?

Lymph-node spread is metastatic disease.

What concept does this question test?

It tests Neoplasia in Pathology. The correct option holds because: Correct: absence of invasion defines in-situ carcinoma.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Neoplasia?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.