Hematology: hemophilia: practice question

A Pediatrics question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pediatrics · Hematology: hemophilia

Sample item

A boy has recurrent painful swollen knees after minor trauma, prolonged aPTT, and normal platelet count. Which condition is most likely?

AVon Willebrand disease onlyBIron deficiency anemiaCImmune thrombocytopeniaDHemophilia A or B

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Hemophilia A or B

Hemophilia causes factor VIII or IX deficiency, leading to deep tissue bleeding and hemarthroses with prolonged aPTT. Factor assays distinguish hemophilia A from B.

Option by option

A. Von Willebrand disease only
Von Willebrand disease more often causes mucosal bleeding and may have variable aPTT.
B. Iron deficiency anemia
Iron deficiency does not cause coagulation-factor deficiency.
C. Immune thrombocytopenia
ITP causes isolated low platelets and mucocutaneous bleeding.
D. Hemophilia A or B (correct)
Correct. Hemarthroses and isolated prolonged aPTT are classic hemophilia findings.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this Pediatrics question

What is the answer to this Pediatrics question?

The best answer is D, Hemophilia A or B. Hemophilia causes factor VIII or IX deficiency, leading to deep tissue bleeding and hemarthroses with prolonged aPTT.

Why is "Von Willebrand disease only" not the answer?

Von Willebrand disease more often causes mucosal bleeding and may have variable aPTT.

Why is "Iron deficiency anemia" not the answer?

Iron deficiency does not cause coagulation-factor deficiency.

Why is "Immune thrombocytopenia" not the answer?

ITP causes isolated low platelets and mucocutaneous bleeding.

What concept does this question test?

It tests Hematology: hemophilia in Pediatrics. Factor assays distinguish hemophilia A from B.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Hematology: hemophilia?

Memorise milestones and the vaccine schedule as tables and revise them often. Then use the flashcards and the other Pediatrics questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.