RNA processing: splicing: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · RNA processing: splicing

Sample item

Which RNA-processing complex removes introns from eukaryotic pre-mRNA and joins the remaining exons?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Spliceosome

The spliceosome is a ribonucleoprotein complex that recognizes splice sites, removes introns as lariats, and joins exons to form mature mRNA. Alternative splicing allows one gene to produce multiple protein isoforms.

Option by option

  • A. Proteasome

    Proteasomes degrade ubiquitinated proteins.

  • B. Ribosome

    Ribosomes translate mature mRNA into protein.

  • C. Spliceosome (correct)

    Correct. The spliceosome carries out pre-mRNA intron removal and exon ligation.

  • D. Telomerase

    Telomerase extends telomeric DNA repeats.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is C, Spliceosome. The spliceosome is a ribonucleoprotein complex that recognizes splice sites, removes introns as lariats, and joins exons to form mature mRNA.

Why is "Proteasome" not the answer?

Proteasomes degrade ubiquitinated proteins.

Why is "Ribosome" not the answer?

Ribosomes translate mature mRNA into protein.

Why is "Telomerase" not the answer?

Telomerase extends telomeric DNA repeats.

What concept does this question test?

It tests RNA processing: splicing in Biochemistry. Alternative splicing allows one gene to produce multiple protein isoforms.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study RNA processing: splicing?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.