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Pediatrics · Nutrition
Sample itemA 10-month-old fed only boiled cow's milk is irritable, refuses to move the legs, and has swollen bleeding gums and subperiosteal haemorrhages. Radiograph shows a ground-glass appearance of bones with a Wimberger ring. Which is the correct treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Oral vitamin C
Infantile scurvy is vitamin C deficiency, which impairs hydroxylation of proline and lysine in collagen. This causes defective connective tissue, bleeding gums, subperiosteal haemorrhage and pseudoparalysis. Radiographic findings include Wimberger ring, Frankel line and Pelkan spurs. Vitamin C produces rapid clinical improvement.
Option by option
A. Vitamin A in high dose
High-dose vitamin A is for xerophthalmia and risks toxicity.
B. Oral vitamin C (correct)
Correct. Vitamin C restores collagen synthesis and reverses the manifestations.
C. Vitamin K injection
Vitamin K deficiency causes bleeding from coagulation defects but not bone changes.
D. Vitamin D with calcium
Vitamin D deficiency causes rickets, with widened and cupped metaphyses.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.