Urology: practice question

A General Surgery question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Surgery · Urology

Sample item

A 65-year-old man has hesitancy, weak stream and nocturia, with a smooth enlarged prostate of 70 grams. Which drug combination reduces the risk of progression and need for surgery?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Tamsulosin with finasteride

In benign prostatic hyperplasia, alpha-1 blockers relax smooth muscle for rapid symptom relief, and 5-alpha-reductase inhibitors shrink the gland over months. Combined therapy reduces progression, acute retention and need for surgery in men with large prostates. Finasteride lowers PSA by about half.

Option by option

  • A. Tadalafil with sildenafil

    Two phosphodiesterase inhibitors are not used and are a hazardous combination.

  • B. Oxybutynin with desmopressin

    Antimuscarinic with desmopressin is used for overactive bladder and nocturnal polyuria and could precipitate retention.

  • C. Bethanechol with finasteride

    Bethanechol stimulates the bladder and does not relieve obstruction.

  • D. Tamsulosin with finasteride (correct)

    Correct. Alpha-blocker plus 5-alpha-reductase inhibitor is the evidence-based combination.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Surgery questions

Questions about this General Surgery question

What is the answer to this General Surgery question?

The best answer is D, Tamsulosin with finasteride. In benign prostatic hyperplasia, alpha-1 blockers relax smooth muscle for rapid symptom relief, and 5-alpha-reductase inhibitors shrink the gland over months.

Why is "Tadalafil with sildenafil" not the answer?

Two phosphodiesterase inhibitors are not used and are a hazardous combination.

Why is "Oxybutynin with desmopressin" not the answer?

Antimuscarinic with desmopressin is used for overactive bladder and nocturnal polyuria and could precipitate retention.

Why is "Bethanechol with finasteride" not the answer?

Bethanechol stimulates the bladder and does not relieve obstruction.

What concept does this question test?

It tests Urology in General Surgery. Combined therapy reduces progression, acute retention and need for surgery in men with large prostates. Finasteride lowers PSA by about half.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Urology?

Learn classic signs and eponyms alongside what they diagnose. Then use the flashcards and the other General Surgery questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.