Nose and paranasal sinuses: olfactory neuroblastoma grading: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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ENT · Nose and paranasal sinuses: olfactory neuroblastoma grading

Sample item

A tumour arising from the olfactory epithelium of the roof of the nose is graded histologically from I to IV according to its architecture, mitoses and necrosis. Which system is used for this histological grade?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Hyams grading

Esthesioneuroblastoma (olfactory neuroblastoma) is graded histologically by the Hyams system, with higher grades having more pleomorphism, mitoses and necrosis and a worse outlook. Kadish staging measures anatomical extent, not histology. Treatment is craniofacial or endoscopic resection with radiotherapy.

Option by option

  • A. Fuhrman grading

    Fuhrman grading is used for renal cell carcinoma.

  • B. Hyams grading (correct)

    Correct. Hyams is the histological grading system for this tumour.

  • C. Kadish staging

    Kadish is a staging system based on extent of spread and not a histological grade.

  • D. Gleason score

    The Gleason score is used for prostate cancer.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this ENT question

What is the answer to this ENT question?

The best answer is B, Hyams grading. Esthesioneuroblastoma (olfactory neuroblastoma) is graded histologically by the Hyams system, with higher grades having more pleomorphism, mitoses and necrosis and a worse outlook.

Why is "Fuhrman grading" not the answer?

Fuhrman grading is used for renal cell carcinoma.

Why is "Kadish staging" not the answer?

Kadish is a staging system based on extent of spread and not a histological grade.

Why is "Gleason score" not the answer?

The Gleason score is used for prostate cancer.

What concept does this question test?

It tests Nose and paranasal sinuses: olfactory neuroblastoma grading in ENT. Kadish staging measures anatomical extent, not histology. Treatment is craniofacial or endoscopic resection with radiotherapy.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Nose and paranasal sinuses: olfactory neuroblastoma grading?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.