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Pediatrics · Systemic paediatrics: idiopathic intracranial hypertension
Sample itemAn obese 13-year-old girl has headaches worse lying down, transient visual obscurations and pulsatile tinnitus. She has bilateral papilloedema, MRI shows no mass, and lumbar puncture shows a markedly raised opening pressure with normal CSF composition. Which is the first-line drug?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Acetazolamide
Idiopathic intracranial hypertension has raised CSF pressure with papilloedema, no mass, and normal CSF composition, and is linked to obesity. Acetazolamide reduces CSF production and is first-line, with weight loss, and surgery or optic nerve sheath fenestration when vision is threatened. Visual fields must be monitored.
Option by option
A. Mannitol
Mannitol is used for acute raised pressure from mass lesions, not long-term treatment.
B. Acetazolamide (correct)
Correct. Acetazolamide lowers CSF production and is the standard first drug.
C. Dexamethasone
Dexamethasone does not help and can worsen weight gain.
D. Sumatriptan
Sumatriptan treats migraine and does not lower intracranial pressure.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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