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Ophthalmology · Uvea: ocular toxocariasis
Sample itemA 7-year-old with a pet puppy has a unilateral white peripheral retinal granuloma with vitreous bands. Ultrasound shows no intralesional calcification. Which test best supports the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. ELISA for antibodies to Toxocara
Ocular toxocariasis from Toxocara canis larvae causes a peripheral granuloma with traction bands in a child with exposure to puppies. The absence of calcification helps to separate it from retinoblastoma, and antibodies are measured by ELISA, ideally in vitreous or aqueous.
Option by option
A. Sabin-Feldman dye test
The Sabin-Feldman dye test detects antibodies to Toxoplasma, which presents differently.
B. ELISA for antibodies to Toxocara (correct)
Correct. ELISA for Toxocara antibodies supports ocular toxocariasis in a child with this lesion.
C. Mantoux test
A Mantoux test supports tuberculosis, which is not the diagnosis here.
D. VDRL test
VDRL is a screening test for syphilis and does not identify a parasitic granuloma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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