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Pediatrics · Paediatric infections: chlamydial pneumonia of infancy
Sample itemA 6-week-old afebrile baby has a staccato cough, tachypnoea and hyperinflated lungs with bilateral infiltrates. The mother reports a purulent eye discharge in the baby during week one. Peripheral eosinophils are raised. Which organism is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Chlamydia trachomatis
Chlamydia trachomatis acquired from the birth canal can cause afebrile pneumonia at 1 to 3 months, with a staccato cough, eosinophilia and often earlier conjunctivitis. Treatment is oral azithromycin or erythromycin. Fever and wheeze would be more typical of RSV bronchiolitis.
Option by option
A. Bordetella pertussis
Pertussis causes whooping paroxysms with lymphocytosis.
B. Chlamydia trachomatis (correct)
Correct. Afebrile staccato cough with eosinophilia after neonatal conjunctivitis points to C. trachomatis.
C. Respiratory syncytial virus
RSV causes wheeze and fever with seasonal outbreaks, without eosinophilia.
D. Pneumocystis jirovecii
Pneumocystis occurs in immunocompromised infants with marked hypoxia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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