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Psychiatry · Mood disorders: antidepressants in young patients
Sample itemWhen an SSRI is started for depression, which group needs particularly close monitoring in the first weeks for emerging suicidal thoughts?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Children, adolescents and young adults
Antidepressants carry a warning of increased suicidal ideation and behaviour in children, adolescents and young adults, mostly in the early weeks of treatment or after a dose change. Risk of this kind has not been shown in older adults.
Option by option
A. Patients with comorbid hypothyroidism
Hypothyroidism is a cause of depression but not a marker for this effect.
B. Postmenopausal women
Menopausal status is not a recognised risk marker for this effect.
C. Children, adolescents and young adults (correct)
Correct. Youth under about 25 years are the group in whom treatment-emergent suicidality is a recognised concern.
D. Patients above 65 years
Older adults do not show an increased risk of this kind with antidepressants.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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