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Psychiatry · Organic mental disorders: transient global amnesia
Sample itemA 62-year-old man suddenly begins repeating the same questions about where he is and what is happening. He knows his name and recognises his wife, has no other neurological signs, and the episode resolves after 8 hours, leaving a gap in memory. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Transient global amnesia
Transient global amnesia is a sudden anterograde amnesia with repetitive questioning, preserved personal identity and no other deficits, lasting up to 24 hours and not recurring often. It is thought to result from transient hippocampal dysfunction.
Option by option
A. Transient global amnesia (correct)
Correct. Self-limited anterograde amnesia with preserved identity is typical.
B. Wernicke encephalopathy
Wernicke encephalopathy includes ophthalmoplegia, ataxia and confusion.
C. Dissociative fugue
Dissociative fugue involves loss of personal identity and purposeful travel after stress.
D. Korsakoff syndrome
Korsakoff syndrome is persistent amnesia with confabulation in chronic alcoholism.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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