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Psychiatry · Eating and sleep disorders: effect of benzodiazepines on sleep stages
Sample itemA polysomnogram is recorded in a patient taking nightly diazepam. Which change in sleep architecture is expected compared with a drug-free night?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. More N2 sleep with reduced N3 and REM
Benzodiazepines shorten sleep latency and increase N2 sleep (with more spindle activity) while suppressing slow-wave N3 and REM sleep. Abrupt withdrawal can cause REM rebound with vivid dreams.
Option by option
A. More N2 sleep with reduced N3 and REM (correct)
Correct. N2 is increased while N3 and REM are suppressed.
B. Prolonged sleep latency with more awakenings
They shorten sleep latency and reduce awakenings.
C. More N3 sleep with increased REM
Benzodiazepines do not increase slow-wave sleep or REM sleep.
D. Reduced N2 sleep with increased REM
REM sleep is reduced, not increased, on benzodiazepines.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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