Gynaecological oncology: granulosa cell tumour: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Gynaecological oncology: granulosa cell tumour

Sample item

A postmenopausal woman has bleeding, an ovarian mass and endometrial hyperplasia. Histology shows Call-Exner bodies. Which marker is useful for follow-up?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Inhibin

Granulosa cell tumours secrete oestrogen, causing endometrial hyperplasia and cancer, and inhibin (and AMH), which is a useful marker. Call-Exner bodies are small follicle-like spaces with a rosette pattern. They can recur late.

Option by option

  • A. Inhibin (correct)

    Correct. Inhibin is the characteristic marker.

  • B. CA-125

    CA-125 is for epithelial tumours.

  • C. LDH

    LDH is for dysgerminoma.

  • D. AFP

    AFP is for yolk sac tumours.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is A, Inhibin. Granulosa cell tumours secrete oestrogen, causing endometrial hyperplasia and cancer, and inhibin (and AMH), which is a useful marker.

Why is "CA-125" not the answer?

CA-125 is for epithelial tumours.

Why is "LDH" not the answer?

LDH is for dysgerminoma.

Why is "AFP" not the answer?

AFP is for yolk sac tumours.

What concept does this question test?

It tests Gynaecological oncology: granulosa cell tumour in OBG. Call-Exner bodies are small follicle-like spaces with a rosette pattern. They can recur late.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gynaecological oncology: granulosa cell tumour?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.