Glaucoma: neovascular: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: neovascular

Sample item

A diabetic patient with ischaemic central retinal vein occlusion presents with a painful eye and rubeosis iridis. What is the mechanism of the raised IOP?

AOverproduction of aqueousBSteroid-induced trabecular damageCFibrovascular membrane over the angle driven by VEGFDPupillary block by a swollen lens

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Fibrovascular membrane over the angle driven by VEGF

Retinal ischaemia releases VEGF, causing new vessels on the iris and angle, which later contract and close the angle. Treatment is panretinal photocoagulation, anti-VEGF and pressure-lowering measures.

Option by option

A. Overproduction of aqueous
The problem is outflow obstruction, not overproduction.
B. Steroid-induced trabecular damage
No steroid use is described.
C. Fibrovascular membrane over the angle driven by VEGF (correct)
Correct. Neovascular membrane closes the angle.
D. Pupillary block by a swollen lens
That mechanism describes phacomorphic glaucoma.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, Fibrovascular membrane over the angle driven by VEGF. Retinal ischaemia releases VEGF, causing new vessels on the iris and angle, which later contract and close the angle.

Why is "Overproduction of aqueous" not the answer?

The problem is outflow obstruction, not overproduction.

Why is "Steroid-induced trabecular damage" not the answer?

No steroid use is described.

Why is "Pupillary block by a swollen lens" not the answer?

That mechanism describes phacomorphic glaucoma.

What concept does this question test?

It tests Glaucoma: neovascular in Ophthalmology. Treatment is panretinal photocoagulation, anti-VEGF and pressure-lowering measures.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: neovascular?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.