Uveitis: juvenile idiopathic arthritis: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Uveitis: juvenile idiopathic arthritis

Sample item

A 4-year-old girl with oligoarticular juvenile idiopathic arthritis has a white quiet eye. Which investigation result puts her at highest risk of chronic anterior uveitis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Positive antinuclear antibody

Young girls with ANA-positive oligoarticular JIA develop an asymptomatic chronic anterior uveitis leading to band keratopathy, synechiae and cataract. Regular slit-lamp screening is therefore needed.

Option by option

  • A. Positive antinuclear antibody (correct)

    Correct. ANA positivity carries the highest uveitis risk.

  • B. Positive rheumatoid factor

    Rheumatoid factor positive polyarticular JIA rarely has uveitis.

  • C. Raised ESR alone

    ESR is nonspecific.

  • D. Positive HLA-B27 in an adult-onset pattern

    HLA-B27 is linked to enthesitis-related arthritis with acute painful uveitis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is A, Positive antinuclear antibody. Young girls with ANA-positive oligoarticular JIA develop an asymptomatic chronic anterior uveitis leading to band keratopathy, synechiae and cataract.

Why is "Positive rheumatoid factor" not the answer?

Rheumatoid factor positive polyarticular JIA rarely has uveitis.

Why is "Raised ESR alone" not the answer?

ESR is nonspecific.

Why is "Positive HLA-B27 in an adult-onset pattern" not the answer?

HLA-B27 is linked to enthesitis-related arthritis with acute painful uveitis.

What concept does this question test?

It tests Uveitis: juvenile idiopathic arthritis in Ophthalmology. Regular slit-lamp screening is therefore needed.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Uveitis: juvenile idiopathic arthritis?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.