Immunisation: immunocompromised child: practice question

A Pediatrics question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pediatrics · Immunisation: immunocompromised child

Sample item

A child with HIV and severe immunosuppression needs polio vaccination. Which is preferred?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Inactivated polio vaccine

In immunocompromised children and their close contacts, IPV is preferred because OPV may cause vaccine-associated paralysis or prolonged excretion. Live vaccines such as BCG are avoided in symptomatic HIV, and measles can be given if CD4 is acceptable. Inactivated vaccines are safe.

Option by option

  • A. Measles vaccine in severe immunosuppression

    Measles vaccine is avoided in severe immunosuppression.

  • B. Inactivated polio vaccine (correct)

    Correct. IPV is safe in immunosuppression.

  • C. BCG

    BCG can cause disseminated disease in symptomatic HIV.

  • D. Oral polio vaccine

    OPV is live and can cause paralysis in immunodeficiency.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pediatrics question

What is the answer to this Pediatrics question?

The best answer is B, Inactivated polio vaccine. In immunocompromised children and their close contacts, IPV is preferred because OPV may cause vaccine-associated paralysis or prolonged excretion.

Why is "Measles vaccine in severe immunosuppression" not the answer?

Measles vaccine is avoided in severe immunosuppression.

Why is "BCG" not the answer?

BCG can cause disseminated disease in symptomatic HIV.

Why is "Oral polio vaccine" not the answer?

OPV is live and can cause paralysis in immunodeficiency.

What concept does this question test?

It tests Immunisation: immunocompromised child in Pediatrics. Live vaccines such as BCG are avoided in symptomatic HIV, and measles can be given if CD4 is acceptable. Inactivated vaccines are safe.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Immunisation: immunocompromised child?

Memorise milestones and the vaccine schedule as tables and revise them often. Then use the flashcards and the other Pediatrics questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.