Drug reactions: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Dermatology · Drug reactions

Sample item

Which of the following drugs is a well-recognised trigger of Stevens–Johnson syndrome and toxic epidermal necrolysis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Carbamazepine

Common triggers include anticonvulsants (carbamazepine, phenytoin, lamotrigine), allopurinol, sulphonamides and nevirapine. HLA-B*15:02 testing is advised before carbamazepine in at-risk populations.

Option by option

  • A. Carbamazepine (correct)

    Correct.

  • B. Metformin

    Metformin rarely does.

  • C. Atenolol

    Atenolol rarely does.

  • D. Amlodipine

    Amlodipine rarely causes severe cutaneous reactions.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Dermatology questions

Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is A, Carbamazepine. Common triggers include anticonvulsants (carbamazepine, phenytoin, lamotrigine), allopurinol, sulphonamides and nevirapine.

Why is "Metformin" not the answer?

Metformin rarely does.

Why is "Atenolol" not the answer?

Atenolol rarely does.

Why is "Amlodipine" not the answer?

Amlodipine rarely causes severe cutaneous reactions.

What concept does this question test?

It tests Drug reactions in Dermatology. HLA-B*15:02 testing is advised before carbamazepine in at-risk populations.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Drug reactions?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.