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Dermatology · Urticaria
Sample itemA 30-year-old woman has recurrent itchy raised red wheals that appear at different body sites. Which feature best supports ordinary urticaria rather than urticarial vasculitis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Each wheal fades within 24 hours and leaves normal skin
In ordinary urticaria, mast cell degranulation causes transient dermal oedema, so each wheal resolves within about a day without residual marks. Urticarial vasculitis lesions last longer, tend to burn, and leave purpura or hyperpigmentation.
Option by option
A. Each wheal fades within 24 hours and leaves normal skin (correct)
Correct. Transient wheals that clear completely are typical of ordinary urticaria.
B. A biopsy shows leukocytoclastic vasculitis
Leukocytoclastic vasculitis on biopsy is the defining feature of urticarial vasculitis.
C. Individual lesions persist for several days and leave bruising or pigmentation
Persistence for days with bruising points to vasculitis, not ordinary urticaria.
D. The lesions burn or are painful rather than itchy
Pain or burning rather than itch is characteristic of urticarial vasculitis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.