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Dermatology · Pigmentary disorders
Sample itemA woman has symmetrical brown patches over the cheeks and forehead. Under Wood's lamp, which finding indicates that the pigment is mainly epidermal?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Enhanced contrast between the lesion and normal skin
Wood's lamp (about 365 nm) accentuates epidermal pigment so that the lesion looks darker against normal skin. Dermal pigment is not enhanced, and a mixed type shows partial enhancement. This helps predict the response to depigmenting agents.
Option by option
A. Coral-red fluorescence of the lesion
Coral-red fluorescence is seen in erythrasma due to porphyrins from Corynebacterium.
B. No change, or reduced contrast, between the lesion and normal skin
Unchanged or reduced contrast suggests a dermal pigment rather than an epidermal one.
C. Enhanced contrast between the lesion and normal skin (correct)
Correct. Epidermal melanin absorbs the long-wave ultraviolet light and is accentuated.
D. Bright apple-green fluorescence of the lesion
Apple-green fluorescence is seen with some tinea capitis and Pseudomonas infection, not with melasma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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