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General Surgery · Perioperative care: postoperative hyponatraemia
Sample itemTwo days after lobectomy for lung cancer, a patient is confused with serum sodium 122 mmol/L, low plasma osmolality, high urine osmolality and normal volume status. What is the first-line management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Fluid restriction
Euvolaemic hyponatraemia with concentrated urine fits SIADH, which follows lung surgery, pain and drugs. Fluid restriction is first line, with slow correction of sodium to avoid osmotic demyelination.
Option by option
A. Fluid restriction (correct)
Correct. Fluid restriction treats SIADH.
B. Rapid large-volume normal saline
Large volumes of saline worsen the dilution when ADH is high.
C. Desmopressin
Desmopressin would aggravate water retention.
D. Rapid 3 percent saline to normal sodium
Rapid correction risks osmotic demyelination.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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