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Pediatrics · Neonatology: pulmonary hypoplasia
Sample itemA newborn with flattened facies, low-set ears and limb deformities is born after pregnancy complicated by severe oligohydramnios. He has severe respiratory distress with a pneumothorax. What is the underlying cause of the breathing problem?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Pulmonary hypoplasia
Prolonged oligohydramnios, as in renal agenesis (Potter sequence), restricts lung growth and leaves hypoplastic lungs. These infants are difficult to ventilate and often develop pneumothorax. Surfactant deficiency occurs with prematurity.
Option by option
A. Transient tachypnoea
Transient tachypnoea is a mild self-limiting problem and does not cause pneumothorax and facial deformity.
B. Pulmonary hypoplasia (correct)
Correct. Lack of amniotic fluid limits lung development, giving pulmonary hypoplasia.
C. Meconium aspiration
Meconium aspiration follows fetal distress in post-term babies.
D. Surfactant deficiency
Surfactant deficiency is a disease of prematurity and not specific to oligohydramnios.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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