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Ophthalmology · Retina: early worsening with glycaemic control
Sample itemA diabetic with HbA1c of 12.5 percent starts intensive insulin. Three months later he has more cotton wool spots and haemorrhages. What is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Transient early worsening after rapid glycaemic improvement
A rapid fall in blood glucose can temporarily worsen retinopathy, and baseline retinal examination before intensification is advised. Long-term control still lowers risk. The other causes lack an exposure in the history.
Option by option
A. Steroid retinopathy
No steroid exposure is described to cause such changes.
B. Transient early worsening after rapid glycaemic improvement (correct)
Correct. Rapid glycaemic improvement can worsen retinopathy transiently.
C. Hypertensive retinopathy
Hypertensive retinopathy needs high blood pressure, which is not described.
D. Radiation retinopathy
Radiation retinopathy needs prior irradiation, which is absent.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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