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Ophthalmology · Neonatal eye disease
Sample itemA newborn develops marked lid swelling and copious purulent discharge from both eyes on the second day of life. Which organism is the most likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Neisseria gonorrhoeae
Gonococcal ophthalmia neonatorum appears within the first few days, is hyperacute and purulent, and can rapidly perforate the cornea. Chlamydial disease appears later, typically in the second week, with milder mucopurulent discharge. Urgent systemic therapy is required.
Option by option
A. Staphylococcus aureus
Staphylococcal conjunctivitis is milder and does not usually cause such a hyperacute picture.
B. Chlamydia trachomatis
Chlamydial conjunctivitis typically begins after the first week and is less purulent.
C. Herpes simplex virus
Herpes simplex usually appears later and may be accompanied by vesicles or keratitis.
D. Neisseria gonorrhoeae (correct)
Correct. Very early hyperacute purulent conjunctivitis suggests gonococcus.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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