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General Surgery · Pancreas
Sample itemA 66-year-old man has progressive painless jaundice, weight loss and a palpable, non-tender gallbladder. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Carcinoma of the head of the pancreas
Courvoisier's law states that a palpable, non-tender gallbladder with jaundice is unlikely to be due to stones. Chronic stone disease leaves a fibrosed, contracted gallbladder that cannot distend. Malignant obstruction, as in a pancreatic head tumour, distends a healthy gallbladder.
Option by option
A. Carcinoma of the head of the pancreas (correct)
Correct. A distal malignant obstruction produces painless jaundice and gallbladder distension.
B. Chronic calculous cholecystitis
Chronic cholecystitis leaves a shrunken gallbladder and rarely causes jaundice.
C. Acute viral hepatitis
Hepatitis does not obstruct the bile duct and would not distend the gallbladder.
D. Gallstone obstruction of the common bile duct
Stones typically cause pain, and the scarred gallbladder does not distend.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.