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Dentistry · Oral pathology: adenoid cystic carcinoma
Sample itemA palatal salivary tumour shows cribriform Swiss cheese growth. The patient has facial pain, and later lung metastases appear years after surgery. Which feature is most characteristic of this tumour?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Perineural invasion
Adenoid cystic carcinoma tends to invade nerves and spreads late to the lung with slow clinical progress. Local recurrence is common because of the perineural spread.
Option by option
A. Rapid nodal spread
Nodal spread is uncommon; haematogenous spread to lung is typical.
B. Origin from Warthin cells
Warthin tumour is a different benign lesion.
C. Perineural invasion (correct)
Correct. Perineural invasion explains the pain and local recurrence.
D. Encapsulated benign behaviour
It is not encapsulated and is a malignant tumour.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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