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Dermatology · Vascular disorders: cutaneous polyarteritis nodosa
Sample itemA young woman has tender subcutaneous nodules and livedo reticularis on the legs for several months, with no renal, neurological or visceral involvement. Biopsy shows medium-vessel necrotising vasculitis. What is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Cutaneous polyarteritis nodosa
Cutaneous polyarteritis nodosa is a skin-limited medium-vessel vasculitis with tender nodules, livedo and ulcers. It follows a relapsing but generally benign course and can follow streptococcal infection. Systemic involvement is absent by definition.
Option by option
A. Erythema nodosum
Erythema nodosum is septal panniculitis without vasculitis.
B. Cutaneous polyarteritis nodosa (correct)
Correct. Skin-limited medium-vessel vasculitis is cutaneous PAN.
C. Classic systemic polyarteritis nodosa
Systemic PAN involves visceral organs.
D. Granulomatosis with polyangiitis
GPA involves the respiratory tract and kidneys with c-ANCA.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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