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Dermatology · Skin tumours: Stewart-Treves syndrome
Sample itemA woman who had a mastectomy with axillary clearance and radiotherapy 10 years ago develops purple nodules on the chronically swollen arm. Biopsy shows malignant vascular channels. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Lymphangiosarcoma (Stewart-Treves syndrome)
Stewart-Treves syndrome is cutaneous angiosarcoma arising in chronic lymphoedema, classically in the arm after mastectomy. It has a poor prognosis, and management is wide excision or amputation with oncological therapy. Early recognition of new purple nodules in a lymphoedematous limb is important.
Option by option
A. Cherry angioma
Cherry angioma is benign.
B. Kaposi sarcoma from HIV
Kaposi sarcoma is HHV-8 related and not arising in chronic lymphoedema.
C. Lymphangiosarcoma (Stewart-Treves syndrome) (correct)
Correct. Angiosarcoma in post-mastectomy lymphoedema is Stewart-Treves syndrome.
D. Pyogenic granuloma
Pyogenic granuloma is benign.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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