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Dermatology · Dermatology: striae distensae
Sample itemA 17-year-old boy who grew rapidly has multiple linear red-purple bands on the lower back that later became pale and atrophic. What is the underlying mechanism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Dermal stretching with rupture of elastic fibres, influenced by cortisol
Striae distensae result from dermal stretching and damage to collagen and elastic fibres in genetically susceptible skin, with raised glucocorticoid levels as a promoter. They appear red or purple (striae rubrae) before turning white and atrophic (striae albae). Persistent purple striae in a patient on steroids or with Cushing syndrome deserve attention.
Option by option
A. Epidermal hyperplasia due to HPV
HPV does not cause striae.
B. Dermal infection with Staphylococcus
They are not infective.
C. Immune complex deposition
Immune complexes are not responsible.
D. Dermal stretching with rupture of elastic fibres, influenced by cortisol (correct)
Correct. Stretching with elastic fibre damage and cortisol influence underlies striae.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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