STI: reactive arthritis skin signs: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · STI: reactive arthritis skin signs

Sample item

A young man with recent urethritis develops asymmetric knee arthritis, conjunctivitis and hyperkeratotic pustular plaques on the soles. What are the sole lesions called?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Keratoderma blennorrhagicum

Reactive arthritis presents with urethritis, conjunctivitis and arthritis, and mucocutaneous signs include keratoderma blennorrhagicum and circinate balanitis. It is strongly linked to HLA-B27 and occurs after chlamydial or enteric infection. Janeway lesions are painless macules in endocarditis.

Option by option

  • A. Janeway lesions

    Janeway lesions occur in infective endocarditis.

  • B. Keratoderma blennorrhagicum (correct)

    Correct. Plantar hyperkeratotic plaques are keratoderma blennorrhagicum.

  • C. Gottron papules

    Gottron papules occur over knuckles in dermatomyositis.

  • D. Pitted keratolysis

    Pitted keratolysis shows crateriform pits in macerated soles without arthritis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is B, Keratoderma blennorrhagicum. Reactive arthritis presents with urethritis, conjunctivitis and arthritis, and mucocutaneous signs include keratoderma blennorrhagicum and circinate balanitis.

Why is "Janeway lesions" not the answer?

Janeway lesions occur in infective endocarditis.

Why is "Gottron papules" not the answer?

Gottron papules occur over knuckles in dermatomyositis.

Why is "Pitted keratolysis" not the answer?

Pitted keratolysis shows crateriform pits in macerated soles without arthritis.

What concept does this question test?

It tests STI: reactive arthritis skin signs in Dermatology. It is strongly linked to HLA-B27 and occurs after chlamydial or enteric infection. Janeway lesions are painless macules in endocarditis.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study STI: reactive arthritis skin signs?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.