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Dermatology · Infections: scurvy
Sample itemA malnourished man has perifollicular haemorrhages with corkscrew hairs, swollen bleeding gums and poor wound healing. Which deficiency is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Vitamin C
Scurvy results from vitamin C deficiency, which impairs hydroxylation of proline and lysine in collagen, leading to perifollicular haemorrhage, corkscrew hairs and bleeding gums. Vitamin K deficiency gives bleeding with deranged coagulation. Treatment is vitamin C replacement.
Option by option
A. Vitamin K
Vitamin K deficiency prolongs prothrombin time but spares collagen.
B. Vitamin A
Vitamin A deficiency causes follicular hyperkeratosis and night blindness.
C. Vitamin B12
B12 deficiency causes megaloblastic anaemia and glossitis.
D. Vitamin C (correct)
Correct. Corkscrew hairs and perifollicular bleeding indicate vitamin C deficiency.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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