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Pathology · Hematopathology
Sample itemWhat is a common feature of acute leukemia?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Blast cells in marrow or blood
Acute leukemia involves clonal proliferation of immature blast cells that replace normal marrow, causing cytopenias and sometimes circulating blasts.
Option by option
A. Only mature lymphocytes
Only mature lymphocytes would not define acute leukemia.
B. High platelets always
Platelets may be low due to marrow failure.
C. No marrow involvement
Bone marrow involvement is central to leukemia.
D. Blast cells in marrow or blood (correct)
Correct: blast proliferation is characteristic of acute leukemia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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